Desloratadine for Allergies

Author: Mary Calvagna, MS

Image for clarinex Desloratadine (Clarinex) is approved for the treatment of perennial allergic rhinitis and long term hives in people aged 6 months and older. For those who suffer from seasonal allergic rhinitis (SAR), the medicine can be used at age 2 and up.

Seasonal Allergic Rhinitis

SAR (or hay fever) occurs during specific times of the year when allergens (things you are allergic to) are in the air. Seasonal allergies are usually at their peak during spring or fall. Perennial allergic rhinitis is related to allergies present year-round, such as cat, dog, or dustmite.

When you breathe in an allergen, cells in your nasal passages release a chemical called histamine. Histamine causes your nose to feel itchy and increases swelling and mucus production in the nasal passages.

The following are symptoms of allergic rhinitis:

  • Sneezing
  • Itching in the nose, eyes, throat, and ears
  • Red, watery eyes
  • Runny nose, nasal congestion
  • Sinus pressure
  • Postnasal drip and cough
  • Headache
  • Dark circles under your eyes

About Desloratadine

Desloratadine is taken once daily. It is a nonsedating antihistamine, which means it blocks the action of the released histamine without making you feel drowsy.

Some of the most common side effects experienced by those taking desloratadine are:

  • Sore throat
  • Dry mouth
  • Sleepiness
  • Fatigue
  • Sore muscles

General Precautions

Clinical studies indicate that people over the age of 65 probably do not need a change in the dose of this medicine. Safety in children younger than 6 months has not been established. In addition, there have been no adequate and well-controlled studies in pregnant women, and desloratadine passes into breast milk. So, if you are pregnant or nursing, talk with your doctor about possible alternative options for treating SAR.

Alternatives

Research is ongoing to develop effective treatments for seasonal allergies. Other antihistamines may help you manage your allergies, such as:

Talk to your doctor about the alternatives and what may work best for you.

Resources:

American Academy of Allergy, Asthma and Immunology

http://www.aaaai.org/

Food and Drug Administration

http://www.fda.gov/

Canadian Resources:

Calgary Allergy Network

http://www.calgaryallergy.ca/

References:

Clarinex package insert. Clarinex website. Available at: http://www.clarinex.com/application. Accessed January 9, 2009.

Desloratadine. EBSCO Health Library website. Available at: http://www.ebscohost.com/thisTopic.php?mar...ID=15&topicID=81. Updated March 2010. Accessed December 17, 2010.

Last reviewed December 2010 by Brian Randall, MD

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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